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Commonwealth Research Commercialization Fund Annual Report, July 1, 2019 – June 30, 2020

Summary

The Commonwealth Research Commercialization Fund (CRCF) Annual Report for July 1, 2019 to June 30, 2020, submitted October 1, 2020 by the Center for Innovative Technology (CIT) as Fund Administrator on behalf of the Virginia Innovation Partnership Authority. The Executive Summary states that between the program's inception in FY2012 and its sunset on June 30, 2020, nearly 380 projects totaling more than $30 million were approved for funding. It reports FY2020 outcomes of approximately $136 million in follow-on monies, nearly $1.7 million in in-kind contributions, eight new companies formed and approximately 49 products or services launched. Appendices cover FY2020 award details, funding totals and RTIAC members.

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“Commonwealth Research Commercialization Fund Annual Report, July 1, 2019 – June 30, 2020.” Archived at Pandemic Darlings, https://pandemicdarlings.com/source-documents/2020-rd388-5d9e7c6798/, SHA-256 79c60a7689a3f6d52e790be6cbfc036ce62123d1f6bfc3e23a805206795f92e2.

Full text

Commonwealth Research
Commercialization Fund
    Advancing Technology and Economic
Development in Virginia by Investing in Priority
  Research and Commercialization Activities
                              ANNUAL REPORT
                        July 1, 2019 – June 30, 2020




                    Submitted by the Fund Administrator:
                      Center for Innovative Technology
          on behalf of the Virginia Innovation Partnership Authority

                              October 1, 2020
Table of Contents

Table of Contents ........................................................................................................................................... i
Executive Summary ....................................................................................................................................... 1
Program Impact ............................................................................................................................................ 1
Program Overview ........................................................................................................................................ 3
FY2020 Solicitation........................................................................................................................................ 4
Program Administration ............................................................................................................................... 5
Preparations for FY2021 ............................................................................................................................... 6
APPENDIX A: FY2020 Award Details.............................................................................................................. 7
APPENDIX B: FY2020 Funding Totals .......................................................................................................... 14
APPENDIX C: RTIAC Members ..................................................................................................................... 15




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Executive Summary

In accordance with Code of Virginia § 2.2-2233.1 G and 2.2-2221 and on behalf of the Virginia Innovation
Partnership Authority (VIPA), the Center for Innovative Technology (CIT) respectfully submits this report
regarding the performance of the Commonwealth Research Commercialization Fund (CRCF) in FY2020.

The CRCF, managed by CIT, accelerated innovation and drove economic development in the
Commonwealth, while solving important state, national, and international problems through technology
research, development, and commercialization. Between the program’s inception in FY2012 and its
sunset on June 30, 2020, nearly 380 projects around the Commonwealth totaling more than $30 million
were approved for funding.

Economic outcomes reported in FY2020 by CRCF award recipients identified early returns on the
Commonwealth’s investment: approximately $136 million in follow-on monies to support further
technology advancement, nearly $1.7 million in in-kind contributions, eight new companies formed, and
approximately 49 products or services launched. In support of the Fund’s goal to commercialize high-
potential technologies, annual outcomes reported by awardees reflect the maturation and evolution of
their organizations and technologies as they advance toward market entry. Outcomes are discussed
below.

In FY2020, CIT offered one CRCF solicitation, which resulted in 30 awards totaling $2.48 million and
leveraging the Commonwealth’s investment with more than $13 million in matching funds. These
projects, along with those in the CRCF portfolio, are being performed by companies, universities, and
research organizations across the state and align with Virginia’s key strategic technology priorities as
outlined in the Commonwealth Research and Technology Strategic Roadmap (hereafter referred to as
“the Roadmap”). The Roadmap, most recently published by the State Council of Higher Education for
Virginia (SCHEV) in October 2019, identifies research areas worthy of economic development and
institutional focus because of their promise of driving economic growth in Virginia.

The FY2020 CRCF program was supported by a $2.8 million General Fund appropriation. Funds available
to award reflected CIT’s administrative fee as well as monies from previous grants that had not been
fully expended or had been declined.


Program Impact

CRCF awards sought to solve current and longstanding global challenges in industries such as life
sciences, cybersecurity, advanced manufacturing, energy, and unmanned systems. CRCF has funded
projects ranging from therapeutics for glioblastoma to transforming agricultural crop protection to

                                                    1
connected and autonomous vehicle solutions to optimizing wireless communications. Among the many
outcomes reported during FY2020, at least one CRCF award recipient was acquired, four organizations
reported Series A investment of more than $3 million and with one receiving $25 million, and several
award recipients were positioned to pivot their CRCF-funded research to help address the COVID-19
pandemic. One organization reported that the National Institutes of Health (NIH) provided funding for
two clinical trials, a Virginia university initiated a preclinical program for the development of a key
peptide, and yet another award recipient reported that they submitted their first Investigational Device
Exemption pre-submission packet. CRCF awardees also reported honors ranging from a National Science
Foundation (NSF) CAREER award, to being selected as a Jefferson Science Fellow to the National
Academies of Science, to receiving the Tibbetts Small Business and Distinguished Researcher awards.
Lastly, an Eminent Researcher Recruitment project has had a crucial role in the establishment of a new
Pharmaceutical Engineering PhD program for one Virginia university. CRCF projects have the potential to
provide a profound and lasting benefit to citizens of the Commonwealth and to society at large by
enhancing quality of life and economic development.

CRCF awards have, primarily, supported early-stage technology development, setting the technology on
a commercialization path and making it attractive for further investment and/or licensing. Milestones
along this often multi-year path include clinical trials; FDA and other regulatory approvals; investment
from federal, private, or other sources; beta product releases; and pilot programs. Fund investments
have resulted in companies created, expanded, or acquired; products launched; revenue generated;
intellectual property developed and licensed; key personnel recruited; and other outcomes beneficial to
Virginia and beyond.

FY2020 reports1 submitted by award recipients demonstrate exciting returns on investment for the
Commonwealth, and aggregate figures are provided below.

                                               Investments

    Follow-on Funding        In-Kind Contributions       Undisclosed Source         Additional Leverage
      $135,586,789                $1,659,148                  $666,000                    $594,769

In FY2020, CRCF awardees reported more than $138 million investment in CRCF-funded technologies,
including follow-on funding, in-kind contributions, and additional leverage. Follow-on funding is
comprised of $72 million in federal grants and $47 million received through capital raises, along with
numerous sources of private funding; an additional $666 thousand was received from undisclosed
sources. For CRCF awardees, in-kind support typically consists of waived salaries or equipment
donations and additional leverage represents monies that awardees reported, beyond their original
match commitment.



1
 FY2020 reports were received between August 16, 2019 and August 15, 2020. Reports provided outcomes for
the awardee’s previous 12 months, or for final reports, for the duration of the project.

                                                     2
                                              Growth and Expansion
                                                                         New Companies          Enhancements
        Revenue                  New Jobs          Jobs Retained
                                                                            Formed            and/or Expansions
      $16,643,667                  168                  162                    8                     29

Three CRCF awardees reported revenue figures of more than $2 million each. One CRCF award recipient
was acquired by a large organization. Along with increasing a physical footprint, a number of award
recipients reported enhancements to their facility and/or equipment.

                                                Products or Services
                                         Anticipated for Release within 12
        Newly Commercialized                                                          Under Development
                                                      Months
                  49                                     90                                     13

In total, 139 products or services were reported as introduced to the market in FY2020 or planned for
release over the next year. Thirteen technologies were reported as under development, including at the
beta, demo, or prototype stages, as well as in pilot programs.

                                               Intellectual Property

                    Patents Granted                                           Patents Pending
                            57                                                      157

CRCF award recipients reported intellectual property creation, including U.S., international, PCT, and
provisional patents. Their reports also cited several patents under development, invention disclosures,
trade secrets, and copyrights. Additionally, several organizations are actively pursuing licensing
agreements for their technology.

Each year CIT assesses and refines CRCF reportable criteria to best reflect the types of economic
outcomes being demonstrated in the Commonwealth. For example, CIT began tracking follow-on
investment and jobs in FY2015; since that time, awardees have reported more than $593 million in
follow-on funding, more than $20 million of in-kind support, more than $105 million in sales and
revenue, and more than 1,800 jobs created or retained.


Program Overview

Since the inception of the CRCF program in FY2012, 1,062 applications were submitted from all nine GO
Virginia regions and, from these submissions, 3782 projects were offered funding. These awards total
more than $30 million and are being leveraged with more than $85 million in matching funds, including
federal awards.

2
    378 projects were offered funding since CRCF’s inception; 20 awards have been declined.

                                                          3
CRCF projects with the potential to positively impact Virginia’s technology future have covered the
following technology sectors: advanced manufacturing, aerospace, communications, cybersecurity,
energy, environment, information technology – including data analytics, life sciences, modeling and
simulation, nuclear physics, transportation, and unmanned systems. Per legislative direction, CRCF
projects advance technology sectors identified in the version of the Roadmap current when a given
solicitation was announced.

CIT leveraged its programs to facilitate company creation and growth. In relation to other CIT programs,
CRCF was part of a pipeline, working closely, for instance, with the Federal Funding Assistance Program
(FFAP), the GAP family of funds, and the Virginia Unmanned Systems Center. CRCF also complemented
other funding programs in the Commonwealth, such as the Virginia Research Investment Fund (VRIF),
the Virginia Catalyst (formerly known as VBHRC, the Virginia Biosciences Health Research Corporation),
the Commonwealth Health Research Board (CHRB), and the Tobacco Region Revitalization Commission.


FY2020 Solicitation

One solicitation was offered in FY2020 that included five programs: Commercialization, Eminent
Researcher Recruitment, Matching Funds, SBIR Matching Funds, and STTR Matching Funds. Applications
were invited from academia, federal labs, other nonprofit research institutions, university research
consortia, and the private sector.

   Commercialization Program
    The Commercialization Program supported validation and commercialization activities for high-
    potential technologies in the proof-of-concept, prototype, or minimum viable product (MVP)
    development phases that had a reasonable probability of enhancing the Commonwealth’s national
    and global competitiveness. The maximum award amount increased from $50,000 to $75,000.

   Eminent Researcher Recruitment Program
    The Eminent Research Recruitment Program supported public colleges and universities seeking to
    acquire or enhance research superiority in qualified technologies through the recruitment of a top
    scholar to its faculty. Research commercialization and collaboration with the private sector are
    important activities for the hired researcher. The maximum award amount was $250,000.

   Matching Funds Program
    The Matching Funds Program enabled public and private higher education institutions, federal labs
    and other nonprofit research institutions in Virginia, and university research consortia that included
    Virginia college and university member institutions to leverage federal, private, or other funds
    designated for the commercialization of high-potential technologies and economic benefit to
    Virginia. The maximum award amount increased from $100,000 to $150,000.


                                                    4
   SBIR and STTR Matching Funds Programs
    The SBIR and STTR Matching Funds Programs accelerated high-potential technology development
    and commercialization efforts by Virginia-based businesses that had recently won a Phase I and/or
    Phase II Small Business Innovative Research (SBIR) or Small Business Technology Transfer (STTR)
    award. The maximum award amount increased from $50,000 to $75,000.

Projects were invited under five technology sectors: clean energy, cybersecurity, data analytics, life
sciences, and unmanned systems.

In FY2020, CIT received 183 eligible Letters of Intent (LOIs) in response to the Request for Proposals
(RFP). Of these, 61 LOIs were approved for application and 49 applications were ultimately received
from 44 discrete organizations and 49 discrete principal investigators. Applicants requested
approximately $4.5 million and these requests spanned all programs and industry sectors and seven of
the nine GO Virginia regions. Thirty awards were announced for $2.48 million, leveraging the
Commonwealth’s investment with more than $13 million in matching funds. Awarded projects also
represented all industry sectors, four of the five programs, and six of the nine GO Virginia regions.

A brief overview of each project announced for award in FY2020 is provided in Appendix A.




Program Administration

Administrative activities in FY2020 included overseeing the solicitation, outreach, and award
management for projects funded in FY2012 through FY2019. The fee for Fund management was
$370,582.

As Fund Administrator and with the support of the Research and Technology Investment Advisory
Committee (RTIAC)3 and the Office of the Secretary of Commerce and Trade, CIT developed the
approach for the FY2020 solicitation, including updated program guidelines, an enhanced application
and review process, and continued use of an online grants management system, CyberGrants, to
facilitate application submission and reporting. CIT led a multi-step review process, starting at the LOI
stage. LOIs were reviewed by CIT for administrative compliance and then underwent a business and
technology-oriented evaluation by external reviewers. Reviewers included members of the RTIAC as well
as investment professionals and other subject matter experts. Applicants whose LOIs were most highly
rated were invited to submit a proposal. Once all proposals were received, CIT performed an internal
compliance review to determine those applications that would advance to examination by subject
matter experts. These experts, including individuals from industry, academia, government, and the
venture capital community, evaluated and rated proposals. Again, those applications that scored highest


3
 The RTIAC is a legislatively-established body comprised of representatives drawn from higher education,
economic development, research institutes, venture capital firms, and technology corporations.

                                                        5
advanced to and were reviewed and ranked by two additional members of the RTIAC. Based on the
assessments of the RTIAC, projects were recommended to the CIT Board of Directors for funding; the
Board made final award decisions, after which awards were announced.

The list of FY2020 RTIAC members is included as Appendix C.

CIT maintains information on the Fund, including awards and current solicitations, on its website,
www.cit.org. In FY2020, press releases announced the request for proposals and, subsequently, award
recipients. Outreach and communications also included social media, email announcements, webinars,
and speaking engagements. Outreach was enhanced by additional communication networks, including
CIT’s GAP team, FFAP, and the Virginia Unmanned Systems Center; Virginia’s regional technology
councils; individual colleges and universities and other higher education institutions; the Virginia
Biotechnology Association (VABIO), regional Association for Unmanned Vehicle Systems International
(AUVSI) chapters, accelerators, investment groups and other organizations that provide support to
entrepreneurs, and economic professionals throughout Virginia.

Following the Governor’s June 2020 press release announcing awards, CIT invited award recipients to
prepare and issue their own press releases. Several awardees pursued the opportunity and CIT
facilitated providing a quote from then-President and CEO, Ed Albrigo. In addition, CIT’s Marketing and
Communications team engaged in outreach to local media outlets and monitored for stories related to
the recent awards. There was coverage from industry press across the state, as well coverage beyond
Virginia.

Also as Fund Administrator, CIT managed awards announced in prior years and produced the FY2019
Annual Report. This included assessing project performance on an ongoing basis. Additionally, CIT
provided support to external organizations, state agencies, and researchers from academia, industry,
and other members of the technology community that desired information about the Fund and future
solicitations. Throughout the year, CIT provided oversight to ensure compliance with the CRCF
guidelines and other requirements.


Preparations for FY2021

In 2020 the General Assembly and Administration created the Virginia Innovation Partnership Authority,
or VIPA. Established by Code of Virginia § 2.2-2351, VIPA brings consolidated and significant strategy,
funding, and oversight for innovation commercialization and entrepreneur support under one entity.
The CRCF program was sunset on June 30, 2020 and transitioned, along with the previously mentioned
VRIF program, to the newly created Commonwealth Commercialization Fund (CCF) per Virginia Code §
2.2-2359. The FY2020 Annual Report of the Virginia Research Investment Committee (VRIC), which
addresses the VRIF, will be submitted separately by SCHEV.




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 APPENDIX A: FY2020 Award Details

                    GO Virginia                                                                                          Period of      Principal       CRCF
Award Recipient                            Project Title                       Project Description                                                               Match
                      Region                                                                                           Performance    Investigator     Award
COMMERCIALIZATION PROGRAM
Commonwealth      Region 7 –          Cloud Search Tool for   CTP’s automated export classification tool will          07/01/2020 –   Mr. Tom        $74,705   $75,029
Trading Partners, Northern            Export Commodity        integrate neural networks and deep learning              04/30/2021     Fergus
Inc.              Virginia            Classification          algorithms to improve efficiency and accuracy in
                                                              determining the export classification of defense
                                                              articles and dual-use commodities, assisting U.S.
                                                              exporters with their compliance requirements under
                                                              the EAR and ITAR.
Cowden              Region 2 –        A Smart Docking         Cowden Technologies is developing a battery              06/15/2020 –   Mr. Mickey     $75,000   $109,000
Technologies, LLC   Roanoke /         Station for Drones      charging and data retrieval docking platform that can    06/14/2021     Cowden
                    New River /                               be installed on a drone and provide autonomous
                    Lynchburg                                 guidance control while docking, undocking, and
                                                              securing the drone to the platform. The technology
                                                              will enable drones to operate remotely without
                                                              human intervention.
Eksdyne Inc.        Region 2 –        A Magnetohydro-         Eksdyne is developing "Flux" actuators – silent,         06/15/2020 –   Mr. Joshua     $74,915   $96,098
                    Roanoke /         dynamic Actuator        configurable, flexible devices responsible for           06/15/2021     Eckstein
                    New River /       System for Robotics     controlling systems with no moving parts, designed
                    Lynchburg                                 for advanced robotic motion.
GATACA LLC          Region 2 –        GAT for NGS: A          CRCF funds will be used to automate and                  06/15/2020 –   Dr. Johanna    $75,000   $76,186
                    Roanoke /         Bioinformatics Tool     commercialize GATACA's bioinformatics product            02/15/2021     Craig
                    New River /       for Hepatitis B Virus   powered by artificial intelligence: GAT/MLv1.0, a
                    Lynchburg         Quasispecies –          novel tool that profiles dangerous mutant strains
                                      Incorporating           from molecular viral populations that perpetuate
                                      Machine Learning        viral infections. GATACA will focus first on the
                                                              Hepatitis B virus.
Lumin               Region 9 –        Promoting Residential   Lumin is proposing to develop a technology capable       07/01/2020 –   Mr. Michael    $64,917   $64,972
                    Greater           Solar PV Development    of automatically keeping solar PV production within a    12/31/2020     Hibshman
                    Charlottesville   Through Curtailment     safe threshold for charging energy storage systems
                                      of Excess Production    during grid outages. This technology will allow solar
                                      Off-Grid                PV systems to be sized according to on-grid
                                                              household needs, without being limited in size by off-
                                                              grid considerations.


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                     GO Virginia                                                                                          Period of      Principal       CRCF
Award Recipient                         Project Title                         Project Description                                                                 Match
                       Region                                                                                           Performance    Investigator     Award
Meru               Region 4 –      Development of the        Meru Biotechnologies is developing cancer                  06/15/2020 –   Mr. Daniel     $75,000   $75,000
Biotechnologies,   Greater         Minimum Viable            biomarkers and opioid detection test kits for their        05/31/2021     Rodenhaver
LLC                Richmond        Product for a Free        novel analytical instrument. This technology will
                                   Solution Biomolecular     provide lower cost and rapid access to lifesaving data.
                                   Characterization
                                   Device
Onclave            Region 7 –      Secure IoT: A Zero-       Onclave Networks is developing a technology that           06/15/2020 –   Mr. James      $75,000   $405,352
Networks, Inc      Northern        Trust Platform for        will enable industries to protect 5G and legacy            06/14/2021     Taylor
                   Virginia        Elimination of OT         systems without rebuilding the network
                                   Attack Surface            infrastructure. Specifically, CRCF funding will allow
                                                             the team to ensure secure integrations, address
                                                             industry integrations, and explore how the
                                                             technology might drive digitalization across industries
                                                             given the sizable projected IoT market.
Organizing4Innov   Region 7 –      Using Team-Learning       Organizing4Innovation is developing a predictive           07/01/2020 –   Dr. Floor      $50,450   $51,595
ation              Northern        and Teamwork-             analytics model with the potential to provide teams        07/01/2021     Blindenbach
                   Virginia        Quality Indicators as     with unique insight into their behavior, allowing them
                                   Objective                 to motivate members to become better innovators
                                   Performance               and team players, helping them to understand what
                                   Assessments to Vet        they do well and where they fall short, and giving
                                   Early-Stage Innovation    them actionable feedback that will help the team
                                   Teams                     perform better.
SCOUT Inc.         Region 7 –      Demonstrating Small       SCOUT is developing an on-site satellite inspection        06/15/2020 –   Mr. Sergio     $74,816   $74,816
                   Northern        Satellite Technology to   technology that will enable small satellites to conduct    12/15/2020     Gallucci
                   Virginia        Enable Satellite Health   autonomous rendezvous, approach, and observation
                                   Inspections in            of spacecraft at resolutions much greater than 100x
                                   Geostationary Orbit       beyond what exists today. CRCF funding will allow
                                                             SCOUT to develop the core of its technology, SCOUT-
                                                             Vision: a high-capability small satellite sensor package
                                                             capable of inspecting objects kilometers away at <1
                                                             cm/px resolution.
Sentinel Robotic   Region 5 –      Sentinel Aerium:          Sentinel Robotic Solutions is developing the Sentinel      07/01/2020 –   Mr. John       $75,000   $75,000
Solutions, LLC     Hampton         American-Made Class       Aerium, a market-disruptive, American-made, vertical       03/31/2021     Robinson
                   Roads           I UAS with Disruptive     takeoff and landing, ruggedized, multi-use, small
                                   Flight Endurance          unmanned aerial system with flight times 3x greater
                                   Technology                than sUAS currently available that will significantly
                                                             expand the uses for small UASs.


                                                                                       8
                     GO Virginia                                                                                        Period of      Principal       CRCF
Award Recipient                           Project Title                        Project Description                                                               Match
                       Region                                                                                         Performance    Investigator     Award
Service Robotics   Region 7 –        A Software Command       SRT is proposing to build a global command center       07/01/2020 –   Dr. Gregory    $75,000    $82,506
& Technologies     Northern          Center for Scheduling    for smart device management, strengthening the          06/30/2021     Scott
                   Virginia          and Optimizing Robots    central controller component of their patent, while
                                     and Humans in Smart      filling an unmet market need for a stand-alone
                                     Buildings                software system that can schedule device
                                                              maintenance and human tasking, prioritized by
                                                              importance for completion and by location within the
                                                              facility.
Techulon Inc       Region 2 –        PPNA-Based               Techulon is developing a platform technology that       07/01/2020 –   Dr. Nrusingh   $75,000    $999,974*
                   Roanoke /         Antimicrobial            makes novel therapeutics accessible to selectively      12/31/2020     Mohapatra
                   New River /       Therapeutics Against     target and kill four groups of pathogens: MRSA,
                   Lynchburg         Multi-Drug-Resistant     Pseudomonas aeruginosa, Klebsiella pneumonia, and
                                     Pseudomonas and          Acinetobacter baumannii, as well as Borelia spp. and
                                     Acinetobacter            Candida spp. With CRCF funding, the team will focus
                                                              on developing a novel peptide-peptide nucleic acids
                                                              (PPNA) targeting A.baumannii.
                                                                                                                                          TOTAL:    $864,803   $2,185,528
MATCHING FUNDS PROGRAM
Old Dominion    Region 5 –           Blockchain-              ODU is seeking to integrate software development        06/15/2020 –   Dr. Sachin     $150,000   $150,000
University      Hampton              Empowered Cyber-         and commercialization activities for Bloxure, a         06/14/2022     Shetty
                Roads                Resilient IoT Security   networked device identity management platform.
                                     Solution                 These efforts will significantly enhance the maturity
                                                              of Bloxure and ensure commercial viability and
                                                              implementation with Sentara Healthcare's
                                                              operational environment at multiple sites.
University of      Region 9 –        Machine Learning         Following a decade of development, UVA has              07/01/2020 –   Dr. Leon       $137,453   $150,000
Virginia           Greater           Technology for           developed and commercialized a system for closed-       06/30/2021     Farhi
                   Charlottesville   Prediction of Future     loop glucose control in Type 1 diabetes. CRCF funding
                                     Glucose Fluctuations     will allow the team to further enhance the system by
                                     to Enable a New          developing a new technology that can predict the
                                     Generation of            next-day glycemic variability for an individual and,
                                     Adaptive Glucose         thereby, enable a new generation of adaptive glucose
                                     Control in Diabetes      control in diabetes with markedly enhanced safety
                                                              and efficacy.
University of      Region 9 –        Novel Automated          Accurate and timely monitoring of plant health status   07/1/2020 –    Dr. Xi Yang    $150,000   $150,000
Virginia           Greater           System to Measure        has a wide range of applications in many areas of the   6/30/2022
                   Charlottesville   Plant Health             Commonwealth and beyond, for example, precision
                                                              agriculture, forestry, and environmental monitoring.

                                                                                       9
                     GO Virginia                                                                                           Period of      Principal       CRCF
Award Recipient                            Project Title                         Project Description                                                                Match
                      Region                                                                                             Performance    Investigator     Award
                                                                UVA is developing a technology to monitor plant
                                                                health automatically or by using an unmanned
                                                                autonomous vehicle.
Virginia            Region 4 –        Development of Novel      VCU is developing a unique catalyst system that can      07/01/2020 –   Dr. Frank      $150,000   $150,000
Commonwealth        Greater           Heterogeneous Cross-      be used in pharmaceutical applications to produce        06/30/2021     Gupton
University          Richmond          Coupling Catalysts for    drug active ingredients. These catalysts are important
                                      Pharmaceutical            because they are not only extremely reactive and
                                      Applications              efficient, but also avoid contamination of the drugs
                                                                with heavy metals.
                                                                                                                                             TOTAL:    $587,453   $600,000
SBIR MATCHING FUNDS PROGRAM
Agrology         Region 7 –           Commercializing a         Agrology is building a precision agriculture system to   06/15/2020 –   Mr. Tyler      $75,000    $750,000*
                 Northern             Precision Agricultural    guide crop farmers to maximum profit and yield with      12/15/2020     Locke
                 Virginia             System for Irrigation,    minimal fertilizer, pest and disease sprays, and
                                      Fertilizer, and Spray     irrigation applications.
                                      Scheduling
Azimuth1            Region 7 –        EnviMetric: Geospatial    Azimuth1 is developing a tool that will show the most    06/15/2020 –   Mr. Jason      $75,000    $995,000*
                    Northern          Statistical Tools for     likely extent of groundwater contamination by            06/15/2021     Dalton
                    Virginia          Environmental             generating statistical estimates of down-gradient
                                      Screening of              distances of contaminant travel to be applied during
                                      Commercial Real           Phase I Environmental Site Assessments for
                                      Estate Sales              commercial real estate transactions.
Babylon Micro-      Region 9 –        Designing a Disruptive    With CRCF funding, Babylon Micro-Farms is proposing      06/15/2020 –   Mr. Graham     $75,000    $223,102*
Farms Inc.          Greater           Platform for              a means to effectively and efficiently automate          11/30/2020     Smith
                    Charlottesville   Hydroponic Vertical       systems of hydroponics. By integrating machine
                                      Farming: Addressing       learning models analyzing plant growth and harvest
                                      Challenges in Effective   yield, the Babylon doser will generate feedback
                                      Urban Farming and         modulating growth conditions and fully automate
                                      the Elimination of        hydroponic operation.
                                      Food Deserts
BEM Controls, LLC   Region 7 –        WiseMrkt: A Platform      BEM Controls will develop a number of algorithms to      07/01/2020 –   Mr. Rasheq     $75,000    $1,049,914*
                    Northern          for Transactive Energy    help building owners improve energy savings and          03/31/2021     Rahman
                    Virginia          and Demand                utilities and better prioritize assets to be optimized
                                      Response Applications     during demand response events.




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                     GO Virginia                                                                                            Period of      Principal         CRCF
Award Recipient                            Project Title                         Project Description                                                                  Match
                        Region                                                                                            Performance    Investigator       Award
Burnshire           Region 8 –        Inverter Controlled       With CRCF funding, Burnshire Hydroelectric will test      07/20/2020 –   Dr. Robert       $74,981   $899,235*
Hydroelectric LLC   Shenandoah        Multigenerator            whether adding an additional generator to a               12/11/2020     Harvey
                    Valley                                      hydropower drive shaft will add range of operation,
                                                                particularly during low river flow periods when typical
                                                                generators cease to operate.
Federal Foundry     Region 7 –        Structured and            CRCF funds will enable Federal Foundry to develop an      06/15/2020 –   Mr.              $73,140   $753,298*
LLC                 Northern          Unstructured HR           analytic tool to help government contracting              06/14/2021     Geoffrey
                    Virginia          Analytics to Support      companies search for and evaluate potential                              Orazem
                                      Hiring, Staffing, and     partners.
                                      Partnership Decision
                                      Making
ICBiome, Inc.       Region 7 –        A WGS-Based               Through federal and prior CRCF funding, ICBiome has       06/15/2020 –   Dr. Srini Iyer   $75,000   $218,843*
                    Northern          Genomics Platform for     developed novel cloud technologies for genomics-          12/15/2020
                    Virginia          Early Identification of   based pathogen diagnostics. Through this latest
                                      MRSA Transmission in      award, the team seeks to develop a visual demo and
                                      ICU Settings              webinar that showcases the success of their SBIR
                                                                Phase 1 MRSA project, as well as a pilot evaluation of
                                                                their genomics surveillance product at a Children's
                                                                Hospital.
KeViRx, Inc         Region 9 –        Development of Novel      CRCF funds will allow KeViRx to further develop a         06/15/2020 –   Dr. John         $75,000   $309,033*
                    Greater           Small Molecule            newly discovered class of small molecules that inhibit    06/14/2021     Lazo
                    Charlottesville   Inhibitors of the         the activity of one of the most potent cancer-causing
                                      Oncogenic Protein         protein tyrosine phosphatases, which is highly
                                      Tyrosine Phosphatase      expressed in ~50% of human malignancies, including
                                      PTP4A3 for the            drug-resistant ovarian cancer and acute myelogenous
                                      Treatment of Human        leukemia.
                                      Cancers
Micro Harmonics     Region 2 –        Cryogenic Isolators for   The design and production of compact cryogenic            06/15/2020 –   Ms. Diane        $75,000   $766,532*
Corporation         Roanoke /         High-Frequency Ship       isolators for use in drone-mounted threat detection       06/14/2021     Kees
                    New River /       Radar and Drone           and structural inspection systems, as well as
                    Lynchburg         Inspection Systems        shipboard radar systems operating at 26-40 GHz, is
                                                                the focus of this Micro Harmonics project. In
                                                                addition, CRCF funding will support innovative new
                                                                methods of producing key ceramic isolator parts by
                                                                using additive manufacturing techniques.




                                                                                         11
                     GO Virginia                                                                                           Period of      Principal       CRCF
Award Recipient                            Project Title                        Project Description                                                                 Match
                        Region                                                                                           Performance    Investigator     Award
ReAlta Life         Region 5 –        Peptide Inhibitor of     This CRCF project will advance the commercial             06/15/2020 –   Dr. Neel       $59,446    $1,497,741*
Sciences            Hampton           Complement C1 (PIC1)     readiness of the PIC1 technology currently under          06/14/2021     Krishna
                    Roads             as a Treatment for       development by ReAlta Life Sciences, as well as
                                      Hypoxic Ischemic         establish quality assurance programs for
                                      Encephalopathy (HIE)     manufacturing and supply of GMP-grade PIC1 and on-
                                                               site evaluation of the Phase I human testing site at
                                                               which first-in-human clinical trials will be conducted.

Tympanogen, Inc.    Region 4 –        Preparation of a         During this project, Tympanogen will prepare the          06/15/2020 –   Dr. Elaine     $75,000    $1,479,163*
                    Greater           510(k) Application for   510(k) application for a novel nonsurgical eardrum        12/31/2020     Horn-
                    Richmond          FDA Clearance of a       repair patch and submit it to the FDA.                                   Ranney
                                      Gel Patch for
                                      Nonsurgical Eardrum
                                      Repair
WynnVision LLC      Region 4 –        Preventing Ventilator-   In the U.S., more than 300,000 patients each year         07/01/2020 –   Dr. Olga       $75,000    $708,940*
                    Greater           Associated Infections    receive mechanical ventilation with a high risk for       06/30/2021     Zolotarskaya
                    Richmond                                   complications and poor outcomes, including death.
                                                               To address this unmet need, WynnVision will use
                                                               CRCF funding to prevent or greatly reduce such
                                                               infections by using an economical treatment for
                                                               silicone endotracheal tubes that kills disease-causing
                                                               pathogens while being nontoxic to human tissue.
                                                                                                                                             TOTAL:    $882,567   $9,725,801
STTR MATCHING FUNDS PROGRAM
AgroSpheres, Inc. Region 9 –          AgroSpheres Enabled      AgroSpheres is developing an RNAi bioinsecticide to       06/15/2020 –   Mr. Ameer      $75,000    $300,000*
                    Greater           RNAi Delivery for        control the invasive Fall Armyworm, one of the most       02/01/2021     Shakeel
                    Charlottesville   Agriculture              common causes of damaged turfgrass.
Li Industries, Inc. Region 2 –        Effective Materials      Li Industries is developing a direct battery recycling    06/15/2020 –   Mr. Nolan      $75,000    $225,000*
                    Roanoke /         Separation for Low-      process that increases the sustainability of the          06/14/2021     Schmidt
                    New River /       Cost Lithium Ion         lithium-ion battery lifecycle by isolating and
                    Lynchburg         Battery Direct           regenerating cathode materials of end-of-life lithium-
                                      Recycling                ion batteries for reuse. This CRCF project aims at
                                                               improving upon and developing new methods of
                                                               separating out the cathode materials to achieve
                                                               higher purity recycled materials.
                                                                                                                                             TOTAL:    $150,000   $525,000
                                                                                                                    TOTAL CRCF FY2020 AWARDS: $2,484,823          $13,036,329

                                                                                        12
APPENDIX B: FY2020 Funding Totals


                                         FY2020 AWARD         FY2020 AWARD          FY2020 MATCH
 PROGRAM
                                                 COUNT                TOTAL                 TOTAL
 Commercialization Program                         12             $864,803            $2,185,528
 Matching Funds Program                             4             $587,453              $600,000
 Eminent Researcher Recruitment                     0                   $0                    $0
 Program
 SBIR Matching Funds Program*                        12            $882,567           $9,725,801
 STTR Matching Funds Program*                         2            $150,000             $525,000
                     ALL PROGRAMS                    30          $2,484,823          $13,036,329

* Matching funds provided toward the CRCF include federal awards and may include additional
awardee-contributed match as well




                                                14
APPENDIX C: RTIAC Members

In FY2020, the following individuals were members of the Research and Technology Investment Advisory
Committee (RTIAC), the group responsible for making CRCF award recommendations to the CIT Board of
Directors.

      Steve Clinton, former Vice President and COO – Sebesta, Inc. (retired)
      Morris Foster, Vice President for Research – Old Dominion University
      Cheryl Giggetts, Principal Consultant – CTA Consultants, LLC
      Keith Holland, Associate Vice Provost for Research, Scholarship and Creative Endeavors – James
       Madison University
      Dennis Manos, Vice Provost for Research and Graduate/Professional Studies – College of
       William and Mary
      Steven Moret, President and CEO – Virginia Economic Development Partnership
      Srirama Rao, Vice President for Research and Innovation – Virginia Commonwealth University
      Venkat Rao, Program Director for Health Market Strategy – Parsons
      Scott Tolleson, Partner – Promethean Investments, LLP
      Craig Wanke, Senior Principal Engineer – The MITRE Corporation




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