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                      Nos. 21A240 & 21A241
________________________________________________________________
________________________________________________________________


           IN THE SUPREME COURT OF THE UNITED STATES

                        _______________


 JOSEPH R. BIDEN, JR., PRESIDENT OF THE UNITED STATES, ET AL.,
                           APPLICANTS

                               v.

                   STATE OF MISSOURI, ET AL.

                        _______________


 XAVIER BECERRA, SECRETARY, UNITED STATES DEPARTMENT OF HEALTH
             AND HUMAN SERVICES, ET AL., APPLICANTS

                               v.

                   STATE OF LOUISIANA, ET AL.

                        _______________


 REPLY IN SUPPORT OF APPLICATIONS FOR STAYS OF THE INJUNCTIONS
  ISSUED BY THE UNITED STATES DISTRICT COURTS FOR THE EASTERN
DISTRICT OF MISSOURI AND WESTERN DISTRICT OF LOUISIANA PENDING
 APPEALS TO THE UNITED STATES COURTS OF APPEALS FOR THE EIGHTH
    AND FIFTH CIRCUITS AND FURTHER PROCEEDINGS IN THIS COURT

                        _______________


                             ELIZABETH B. PRELOGAR
                               Solicitor General
                                 Counsel of Record
                               Department of Justice
                               Washington, D.C. 20530-0001
                               SupremeCtBriefs@usdoj.gov
                               (202) 514-2217


________________________________________________________________
________________________________________________________________
            IN THE SUPREME COURT OF THE UNITED STATES

                         _______________


                           No. 21A240

 JOSEPH R. BIDEN, JR., PRESIDENT OF THE UNITED STATES, ET AL.,
                           APPLICANTS

                               v.

                    STATE OF MISSOURI, ET AL.

                         _______________


                           No. 21A241

 XAVIER BECERRA, SECRETARY, UNITED STATES DEPARTMENT OF HEALTH
             AND HUMAN SERVICES, ET AL., APPLICANTS

                               v.

                   STATE OF LOUISIANA, ET AL.

                         _______________


  REPLY IN SUPPORT OF APPLICATIONS FOR STAYS OF THE INJUNCTIONS
   ISSUED BY THE UNITED STATES DISTRICT COURTS FOR THE EASTERN
 DISTRICT OF MISSOURI AND WESTERN DISTRICT OF LOUISIANA PENDING
 APPEALS TO THE UNITED STATES COURTS OF APPEALS FOR THE EIGHTH
    AND FIFTH CIRCUITS AND FURTHER PROCEEDINGS IN THIS COURT

                         _______________


    Hospitals, nursing homes, and other healthcare providers that

choose to participate in Medicare and Medicaid have long been

subject to detailed conditions adopted by the Secretary of Health

and Human Services (HHS) -- including rules issued under the Sec-

retary’s express statutory authority to protect the health and
                                  2

safety of Medicare and Medicaid patients.     In response to an un-

precedented pandemic, the Secretary adopted an additional health

and safety condition requiring covered facilities to ensure that

their staff are vaccinated against COVID-19 (subject to medical

and religious exemptions).    Such vaccine requirements had already

been adopted by many healthcare providers and public-health agen-

cies around the country and are overwhelmingly supported by the

medical community.    And the Secretary determined that vaccination

of healthcare staff is the most effective way to prevent the

transmission of a highly communicable and dangerous virus to pa-

tients who are especially vulnerable to its deadly effects.

     As the Eleventh Circuit concluded in a comprehensive pub-

lished opinion, respondents’ various challenges to the rule are

unlikely to succeed.    Most importantly, the rule falls squarely

within the Secretary’s statutory authority.    Respondents scarcely

dispute that requiring facilities to ensure that staff are vac-

cinated against COVID-19 qualifies as a measure to protect pa-

tients’ “health and safety” within the plain meaning of those

terms.   42 U.S.C. 1395x(e)(9); see pp. 5-6, infra (additional

statutes conferring authority).       Instead, respondents ask this

Court to depart from ordinary principles of statutory interpreta-

tion by demanding a clear statement specifically authorizing a

vaccination requirement.    That approach has no foundation in this

Court’s precedents.    This is not a case where an agency is acting

outside its expertise or regulating in an area Congress has not
                                   3

authorized.   Nor do these cases involve any federal intrusion into

matters reserved to the States.        Instead, a federal healthcare

agency adopted a familiar health and safety requirement to protect

patients in the federal healthcare programs the agency adminis-

ters, pursuant to express statutory authority to do just that.

     The equities overwhelmingly support stays pending appeal.

The ongoing COVID-19 surge has driven case rates to new highs --

up more than fourfold since the Secretary issued the rule in early

November and nearly threefold since the government filed its

applications just over two weeks ago.       See Centers for Disease

Control   and     Prevention      (CDC),    COVID     Data    Tracker,

https://go.usa.gov/xeFyx.     The rule has never been more necessary

than it is now, as the virtually unanimous support of healthcare

organizations demonstrates.    Absent stays, the preliminary injunc-

tions will likely result in hundreds or thousands of deaths and

serious illnesses from COVID-19 that could otherwise be prevented.

Respondents’ speculative assertions about the rule’s effect on

staffing pale in comparison to the overwhelming public interest in

saving lives and preventing serious illness.    Stays pending appeal

are both wholly warranted and urgently needed.

I.   This Court Would Likely Grant Review If Either Court Of Ap-
     peals Affirmed One Of The Preliminary Injunctions

     This Court would likely grant review if a court of appeals

upheld one of the preliminary injunctions.          Respondents do not

seriously dispute that the validity of the rule is a question of
                                       4

exceptional national importance.           Cf. Missouri Opp. 9 & n.7; Lou-

isiana Opp. 39.       Nor do they deny that the Fifth and Eighth Cir-

cuits’ orders denying stays directly conflict with a published

decision of the Eleventh Circuit holding that “the Secretary was

authorized to promulgate the interim rule.”            Florida v. HHS, 19

F.4th 1271, 1287 (2021).         And a rule to protect patients in the

nationwide Medicare and Medicaid programs in response to an ongoing

public health emergency is in effect in only half the States.         That

is a paradigmatic basis for review.1

II.   The Government Is Likely To Succeed On The Merits

      The rule is squarely within the Secretary’s express statutory

authority, constitutionally sound, thoroughly explained, and pro-

cedurally valid.

      A.    The Rule Falls Within The Agency’s Statutory Authority

      Respondents’ central argument (Missouri Opp. 10-24; Louisiana

Opp. 14-16, 22-26) is that requiring facilities that accept federal

Medicare and Medicaid funds to ensure their staff are vaccinated

against    COVID-19    exceeds   the   Secretary’s   statutory   authority.

They are mistaken.




      1   The Louisiana respondents note (Opp. 39) that Florida
has tried to renew its request for an injunction pending appeal
before the en banc Eleventh Circuit. But that court has neither
called for a response nor taken any other action on Florida’s
request in the more than two weeks since it was filed.
                                      5

            1.   The rule is authorized by the plain text of the
                 relevant statutes

     a.     The rule invokes the Secretary’s statutory authority to

make “rules and regulations          * * *   as may be necessary to the

efficient administration of the functions with which [he] is

charged under” the Medicare and Medicaid programs.             42 U.S.C.

1302(a); see 42 U.S.C. 1395hh(a)(1).         But respondents err in im-

plying (e.g., Louisiana Opp. 24) that the rule rests exclusively

-- or even primarily -- on that general authority.           To the con-

trary, the Secretary also invoked additional authorities specifi-

cally applicable to each category of facility covered by the rule.

86 Fed. Reg. 61,555, 61,567 (Nov. 5, 2021); see ibid. (table set-

ting forth statutes); id. at 61,575-61,583 (detailed discussion).

And the statutory provisions applicable to the vast majority of

those facilities expressly authorize the Secretary to impose re-

quirements to protect the “health” and “safety” of patients.

     The provision governing hospitals, for example, provides au-

thority to impose “requirements as the Secretary finds necessary

in the interest of the health and safety of individuals who are

furnished services in the institution.”           42 U.S.C. 1395x(e)(9)

(emphasis added); see 42 U.S.C. 1395i-3(d)(4)(B), 1396r(d)(4)(B)

(analogous authority for long-term care facilities); 42 U.S.C.

1395k(a)(2)(F)(i), 1395l(i)(1)(A) (ambulatory surgery centers); 42

U.S.C. 1395x(dd)(2)(G) (hospices); 42 U.S.C. 1395x(o)(6) (home

health    agencies);   42   U.S.C.   1395x(ff)(3)(B)   (community   mental
                                   6

health centers); 42 U.S.C. 1395eee(f)(4) (programs of all-inclu-

sive care for the elderly); 42 U.S.C. 1395x(cc)(2)(J) (comprehen-

sive     outpatient   rehabilitation     facilities);   42      U.S.C.

1395x(p)(4)(A)(v) (providers of certain outpatient therapies); 42

U.S.C. 1395x(aa)(2)(k) (rural health clinics).     For some of those

facilities, Congress conferred on the Secretary not only the au-

thority to impose health and safety requirements, but a “duty and

responsibility” to do so.   42 U.S.C. 1395i-3(f)(1) (long-term care

facilities); see 42 U.S.C. 1395bbb(b) (home health agencies).

       The rule’s vaccination “requirement[]” protects “the health

and safety of” patients within the plain meaning of those statutes.

42 U.S.C. 1395x(e)(9).    Most immediately -- and most importantly

-- requiring facilities to ensure that healthcare workers are vac-

cinated against COVID-19 substantially reduces the likelihood that

those workers will contract the virus and transmit it to patients.

86 Fed. Reg. at 61,558; see ibid. (citing study finding that vac-

cination was “80 percent effective in preventing    * * *    infection

among frontline workers”).       That protection is especially im-

portant for Medicare and Medicaid beneficiaries, who are dispro-

portionately vulnerable to severe negative outcomes from COVID-

19.    Id. at 61,566, 61,568.   And it is particularly necessary in

healthcare facilities, where close contact is inevitable and phys-

ical distancing is often impossible, id. at 61,577 -- and where

patients typically have no practical ability to avoid exposure to

unvaccinated staff members.     Requiring facilities to ensure staff
                                7

vaccination also protects patient health and safety by eliminating

a basis for patients to defer other medical care to avoid exposure

to unvaccinated staff.    Id. at 61,558.    And it reduces staff

infections and the resulting “absenteeism due to COVID-19-related

exposures or illness,” which can “create staffing shortages that

disrupt patient access to recommended care.”   Id. at 61,559.

     Those direct and vital protections for patient health and

safety explain the nearly universal support for the rule expressed

by medical and public-health organizations in the joint statement

relied upon by the Secretary, 86 Fed. Reg. at 61,565, and the

multiple amicus briefs filed in support of the government’s ap-

plications from a variety of perspectives, see American Medical

Ass’n (AMA) Amici Br. (more than a dozen associations representing

medical professionals and patients); American Public Health Ass’n

(APHA) Amici Br. (wide range of public-health scholars and deans);

Former Federal Health Officials Amici Br. (leaders of HHS and the

Centers for Medicare & Medicaid Services during the Clinton, George

W. Bush, and Obama Administrations); Service Employees Int’l Union

(SEIU) Amici Br. (labor representatives of hundreds of thousands

of healthcare workers).

     b.   Respondents offer no reason to doubt that requiring fa-

cilities to ensure that healthcare workers are vaccinated against

COVID-19 advances patient “health” and “safety” within the plain

meaning of the relevant statutes. The Missouri respondents contend

(Opp. 14-18) that the statutory requirement that a hospital comply
                                        8

with “such other requirements as the Secretary finds necessary in

the    interest       of   [patient]   health    and   safety,”   42   U.S.C.

1395x(e)(9), must be construed in light of the other requirements

in Section 1395x(e).         And they assert (Opp. 17) that the rule “is

materially unlike the requirements listed in the preceding eight

provisions”      of   that   statute   because   those   provisions    “impose

structural requirements on hospitals themselves” not on “hospital

staff.”      But the rule likewise operates on the hospital, not its

staff:       “The hospital must develop and implement policies and

procedures to ensure that all staff are fully vaccinated for COVID-

19.”       42 C.F.R. 482.42(g) (emphasis added).         And to the extent

respondents mean that the rule requires hospitals to ensure that

their staff meet a specified standard or take specified actions,

that does not distinguish it from many other requirements imposed

by and under the authority of Section 1395x(e).2

       c.     Respondents also observe (e.g., Missouri Opp. 13 & n.8)

that a few of the facility-specific statutes the Secretary invoked

-- which apply to less than three percent of all workers covered



       2  See, e.g., 42 U.S.C. 1395x(e)(1) (requiring that care be
provided “by or under the supervision of physicians,” who are
defined in Section 1395x(r) as doctors meeting specified licensing
and other requirements); 42 U.S.C. 1395x(e)(5) (requiring hospi-
tals to have “a licensed practical nurse or registered professional
nurse on duty at all times”); 42 C.F.R. 482.15(d)(1)(i) (requiring
hospitals to provide “training in emergency preparedness policies
and procedures to all new and existing staff”); 42 C.F.R.
482.42(c)(2)(iv) (requiring training of “hospital personnel and
staff” on “infection prevention and control guidelines, policies,
and procedures”).
                                       9

by the rule -- do not expressly refer to health and safety.3             But

the statutes respondents cite (ibid.) include broadly worded del-

egations of authority for the Secretary to set, e.g., “standards”

or “requirements” for the facilities’ participation in Medicare or

Medicaid.   See 42 U.S.C. 1396d(h)(1) (authority to set “standards”

for   psychiatric    residential      treatment   facilities);   42   U.S.C.

1396d(d)(1) (authority to set “standards” for intermediate care

facilities for individuals with intellectual disabilities (ICFs-

IID)); 42 U.S.C. 1395rr(b)(1)(A) (authority to set “requirements”

for   end-stage     renal   disease     (ESRD)    facilities);   42   U.S.C.

1395x(iii)(3)(D)(i)(IV) (authority to set “requirements” for home

infusion therapy suppliers).

      Because, as shown above, the Secretary’s authority to set

health and safety requirements includes authority to require vac-

cination of staff at covered Medicare and Medicaid facilities, the

broadly worded authorities conferred by the statutes that respond-

ents cite do as well.       Indeed, the Secretary has long exercised

the authorities in those statutes to impose health and safety

requirements for the covered facilities generally -- and, in some



      3   Respondents point to four categories of facilities cov-
ered by statutes that do not include express health and safety
language: (1) psychiatric residential treatment facilities, which
have an estimated total of 30,000 staff; (2) intermediate care
facilities for individuals with intellectual disabilities, which
have an estimated total of 80,000 staff; (3) end-stage renal dis-
ease facilities, which have an estimated total of 170,000 staff;
and (4) home infusion therapy suppliers, which have an estimated
total of 20,000 staff. 86 Fed. Reg. at 61,603.
                                10

cases, infection-control requirements in particular.    See, e.g.,

42 C.F.R. 483.470(l)(1) (infection-control requirements for ICFs-

IID); 42 C.F.R. 494.30 (same for ESRD facilities). The requirement

at issue here falls comfortably within those same authorities.4

          2.   Respondents offer no basis to depart from the plain
               meaning of the statutory text

     Because the requirement that Medicare and Medicaid facilities

ensure that their staff are vaccinated against a highly transmis-

sible and deadly virus is so readily understood as an exercise of

the “health and safety” and other statutory authorities conferred

on the Secretary, respondents repeatedly return to the assertion

that the Court should impose on Congress a heightened-specificity

requirement demanding an express reference to vaccination.   There

is no basis for that departure from the text.

     a.   Respondents principally rely (Missouri Opp. 22-23; Lou-

isiana Opp. 22-23) on what they call the “major-questions doc-

trine.”   But this case lacks the hallmarks of the decisions re-

spondents invoke, all of which grounded their analysis in the text,

structure, and context of the relevant statutes.   Here, HHS is not

asserting regulatory power that is “markedly different” from the

type of authority that Congress expressly identified in the rele-

vant provision, Alabama Ass’n of Realtors v. HHS, 141 S. Ct. 2485,

     4    Even if it did not, that would at most justify an in-
junction against enforcement of the few portions of the rule that
rest on statutes without express health and safety language. See
86 Fed. Reg. at 61,560 (“To the extent a court may enjoin any part
of the rule, the Department intends that other provisions or parts
of provisions should remain in effect.”).
                                   11

2488 (2021) (per curiam); or trying to regulate in an area Congress

has affirmatively rendered off-limits in more specific legislation

directly addressing the issue, cf. FDA v. Brown & Williamson To-

bacco Corp., 529 U.S. 120, 143 (2000); or claiming authority that

would “render the statute ‘unrecognizable to the Congress that

designed’ it,” Utility Air Regulatory Grp. v. EPA, 573 U.S. 302,

324 (2014) (citation omitted); see id. at 321, 324 (observing that

under EPA’s interpretation, “annual permit applications would jump

from about 800 to nearly 82,000,” causing “construction projects

to grind to a halt nationwide”).        Nor is this a case where an

agency responsible for public health has attempted to regulate

“the landlord-tenant relationship,” Alabama Ass’n, 141 S. Ct. at

2489, or a tax agency has made “health insurance policy,” King v.

Burwell, 576 U.S. 473, 486 (2015).       Instead, the federal agency

primarily responsible for health care is setting health and safety

requirements   for   facilities   participating   in   federally   funded

healthcare programs, pursuant to an express statutory authoriza-

tion to do just that.

     The Secretary’s exercise of that authority to require Medi-

care and Medicaid facilities to ensure their workers are vaccinated

in no way renders the relevant statutes “unrecognizable.”          Utility

Air, 573 U.S. at 324 (citation omitted). To the contrary, Congress

authorized the Secretary to adopt health and safety requirements

he finds necessary precisely because it understood that it could

not foresee and “include in the legislation” all requirements that
                                12

might prove necessary to protect patients from hazards like “con-

tagion.”   H.R. Rep. No. 213, 89th Cong., 1st Sess. 25-26 (1965).

Nor is there anything “breathtaking,” Alabama Ass’n, 141 S. Ct. at

2489, or “extravagant,” Utility Air, 573 U.S. at 324, about the

Secretary’s determination that requiring Medicare- and Medicaid-

funded facilities to adopt the measure most likely to prevent

transmission of a potentially deadly virus to vulnerable patients

is necessary for those patients’ health and safety.

     Respondents rely heavily on the asserted “economic and po-

litical significance” of the rule.   Louisiana Opp. 22 & n.6 (ci-

tations omitted); see Missouri Opp. 1, 20.   But this Court regu-

larly decides challenges to agency actions of major economic and

political significance under the usual rules of statutory inter-

pretation, without imposing heightened-specificity requirements.

See, e.g., Collins v. Yellen, 141 S. Ct. 1761, 1776 (2021); Little

Sisters of the Poor Saints Peter & Paul Home v. Pennsylvania, 140

S. Ct. 2367, 2380-2381 (2020); Department of Commerce v. New York,

139 S. Ct. 2551, 2571-2572 (2019); cf. Trump v. Hawaii, 138 S. Ct.

2392, 2408 (2018).   Likewise, although the scope of the Medicare

program inevitably means that the Secretary’s determinations may

involve billions of dollars, see Azar v. Allina Health Servs., 139

S. Ct. 1804, 1808 (2019), this Court has never treated that as a

reason to demand a specific authorization in a Medicare case.

Respondents thus err in presuming that the mere fact that a rule
                                  13

could be called “economically and politically significant” re-

quires Congress to have specifically referred to the precise reg-

ulatory measures in the statute authorizing the agency action.

     Respondents also emphasize (e.g., Missouri Opp. 21) that HHS

has not previously exercised the statutory authorities at issue

here to condition funding on policies requiring vaccination.     But

HHS has never before faced a situation like this one:    a pandemic

driven by an infectious disease that poses especially lethal

threats to patients at healthcare facilities, that can be prevented

through widely available and highly effective vaccines, and for

which near-universal vaccination has not already been achieved

through other means (such as the ubiquitous vaccination require-

ments imposed by schools).    86 Fed. Reg. at 61,567-61,569.   In the

context of that unprecedented threat to patient health and safety,

a vaccination requirement is simply a specific, urgently needed

application of HHS’s longstanding requirements that facilities

take active measures to prevent the spread of “infections and

communicable diseases.”      51 Fed. Reg. 22,010, 22,027 (June 17,

1986); see, e.g., 42 C.F.R. 482.42 (current infection-control re-

quirements for hospitals); 42 C.F.R. 483.80 (long-term care fa-

cilities); 42 C.F.R. 484.70(b) (home health agencies); 42 C.F.R.

416.51 (outpatient surgery centers); 42 C.F.R. 418.60 (hospices);

42 C.F.R. 494.30 (ESRD facilities).

     Vaccination requirements are, moreover, familiar measures

that have long been common in a variety of contexts.    See Missouri
                                 14

Appl. 22-23.   “Healthcare facilities across the country” require

workers to be vaccinated for other infectious diseases, including

hepatitis B, influenza, and measles, mumps, and rubella.              CDC,

State Healthcare Worker and Patient Vaccination Laws (Feb. 28,

2018),   https://go.usa.gov/xtxxT;    see   86   Fed.   Reg.   at   61,567-

61,568; Florida, 19 F.4th at 1288.      Those common requirements to

prevent the spread of dangerous infectious disease in healthcare

settings reflect the “ethical duty” of healthcare workers “to pro-

tect those they encounter in their professional capacity,” 86 Fed.

Reg. at 61,569 -- a modern fulfillment of the ancient admonition

that a healer should first do no harm. The vaccination requirement

here rests on those deep foundations and thus is in no way “un-

precedented” as a health and safety measure.        Alabama Ass’n, 141

S. Ct. at 2489.

     It is instead respondents who seek an unprecedented result

here -- a holding that, even though the text of the relevant

statutory authorities clearly covers the health and safety re-

quirement at issue, some heightened measure of specificity is re-

quired simply because the rule has engendered some undefined meas-

ure of political disagreement.   Agencies are not permitted “to act

unlawfully even in pursuit of desirable ends,” Alabama Ass’n, 141

S. Ct. at 2490, but neither are they disabled from acting lawfully

simply because some find the ends undesirable.          To rely on such

“extratextual sources” would “risk amending statutes outside the

legislative process reserved for the people’s representatives,”
                                 15

thereby undermining, not furthering, separation-of-powers princi-

ples.     Bostock v. Clayton County, 140 S. Ct. 1731, 1738 (2020);

accord id. at 1824 (Kavanaugh, J., dissenting).

     b.     Respondents also rely on the proposition that extra

statutory clarity is required when an agency seeks to “signifi-

cantly alter the balance between federal and state power.”   Loui-

siana Opp. 22 (citation omitted); see Missouri Opp. 20-21, 23-24.

That argument is misplaced.   The rule is a condition on facilities

participating in federal spending programs, and States have no

power to set conditions on federal activities.    See, e.g., McCul-

loch v. Maryland, 17 U.S. (4 Wheat.) 316, 436 (1819).     The rule

accordingly does not alter or override the “constitutional balance

of federal and state powers.” Missouri Opp. 20 (citation omitted).

     Respondents observe (e.g., Missouri Opp. 24) that this Court

has held that the federal government’s spending power does not

allow it to coerce States into adopting regulatory policies or to

impose conditions on States’ acceptance of federal funds without

clear notice.     But those constitutional limitations (which, as

discussed below, are in no way exceeded here) do not imbue the

States with any power over federal spending programs.   See, e.g.,

Sabri v. United States, 541 U.S. 600, 608 n.* (2004) (explaining

that the federal spending power applies with equal force when

Congress legislates “in an area historically of state concern”).

Because conditions on federal spending programs are in no sense
                                     16

“the particular domain of state law,” Alabama Ass’n, 141 S. Ct. at

2489, respondents’ federalism-canon arguments fail.

     c.    For   similar   reasons,       respondents’   argument    that   a

heightened-specificity requirement applies because the rule “in-

vokes the outer limits of Congress’ power,” Missouri Opp. 20 (ci-

tation omitted) -- and their related argument that the rule vio-

lates the Constitution, see Louisiana Opp. 26-28 -- are meritless.

     As previously explained (see, e.g., Missouri Appl. 28-29),

the vaccination condition at issue here -– like countless other

conditions of participation in Medicare and Medicaid -- reflects

a straightforward exercise of Congress’s spending power.             Respond-

ents do not seem to dispute that basic point.              And respondents

cannot    deny   that   protecting    patients     in    federally    funded

healthcare programs from a deadly virus furthers the “general Wel-

fare of the United States.”     U.S. Const. Art. I, § 8, Cl. 1; see,

e.g., South Dakota v. Dole, 483 U.S. 203, 206–207 (1987).

     The Louisiana respondents instead invoke the principle that

the conditions of federal grants to States must be clear.                Opp.

26-27 (citing Pennhurst State Sch. & Hosp. v. Halderman, 451 U.S.

1, 17 (1981)).     The conditions at issue here fully comply with

that principle.    As an initial matter, the vast majority of the

facilities subject to the condition are private entities partici-

pating in Medicare and Medicaid -- not States.            Those conditions

apply to state-run hospitals and other facilities only in the same

manner as they apply to federally funded facilities generally.
                                  17

And in any event, the relevant statutes make perfectly clear that

participation in Medicare and Medicaid is conditioned on compli-

ance with, e.g., “requirements [that] the Secretary finds neces-

sary in the interest of the health and safety” of patients.           42

U.S.C. 1395x(e)(9) (hospitals).

     Respondents seem to suggest that Congress was required not

only to clearly condition participation on compliance with health

and safety conditions adopted by the Secretary, but also to clearly

set forth all the detailed conditions in the statute itself.         But

this Court has never imposed such a requirement, which would rad-

ically alter the administration of Medicare, Medicaid, and count-

less other spending programs.     Medicare’s “Conditions of Partici-

pation” for hospitals alone span some 48 pages in the Code of

Federal Regulations.     42 C.F.R. Pt. 482.         To take just a few

examples, those conditions address such matters as hospital gov-

ernance,   hiring,   staffing,   and   budgeting,   42   C.F.R.   482.12,

482.22; patients’ rights, including grievance procedures and lim-

its on the use of restraints, 42 C.F.R. 482.13; emergency prepar-

edness, 42 C.F.R. 482.15; recordkeeping, 42 C.F.R. 482.24; and the

hospital’s physical environment, down to the placement of hand

sanitizer, 42 C.F.R. 482.41(b)(8).       On respondents’ view, all of

those conditions are invalid because they are not specifically set

forth in the statute.5

     5    To the extent respondents suggest that the rule coerces
them in any way (cf. Louisiana Opp. 27), they are mistaken. Unlike
the Medicaid expansion the Court held to be impermissibly coercive
                                 18

     The Louisiana respondents’ cursory assertion (Opp. 27) that

any statutory provision authorizing the vaccination rule is “an

unconstitutional delegation of legislative authority” is similarly

baseless.    As noted above, the rule is an exercise of the Secre-

tary’s statutory authorities to impose conditions -- including, in

most cases, “requirements    * * *     necessary in the interest of

[patient] health and safety,” 42 U.S.C. 1395x(e)(9) -- for entities

participating in Medicare and Medicaid.      Those statutes readily

provide the “intelligible principle[s]” required by this Court’s

non-delegation decisions.    Whitman v. American Trucking Ass’ns,

531 U.S. 457, 474 (2001) (citation omitted); see id. at 475 (find-

ing that direction to regulate “to protect the public health”

sufficiently guided the agency’s exercise of discretion); see also

Gundy v. United States, 139 S. Ct. 2116, 2129 (2019) (plurality

opinion) (collecting examples).       Respondents do not attempt to

reconcile their claim with those precedents.

     d.     In one final effort to justify a departure from the

statutory text, respondents contend (Missouri Opp. 18-19, 23; Lou-

isiana Opp. 14-16) that the rule conflicts with 42 U.S.C. 1395.



in National Federation of Independent Business v. Sebelius, 567
U.S. 519, 541-542 (2012), the rule regulates Medicare and Medicaid
facilities, not States. And contrary to the Missouri respondents’
assertion (Opp. 6), HHS does not “force[] ‘State surveyors . . .
to assess compliance with’” the vaccination requirement. A State’s
decision to enter into a survey agreement with the Secretary is
voluntary. See 42 U.S.C. 1395aa(a) (“The Secretary shall make an
agreement with any State which is able and willing to do so[.]”)
(emphasis added).
                                  19

But respondents misread Section 1395.        That provision, titled

“Prohibition against any Federal interference,” provides that fed-

eral officials may not exercise “supervision or control over,”

inter alia, “the practice of medicine,” the “selection, tenure, or

compensation of” healthcare workers, or “the administration or

operation” of healthcare facilities.    Ibid.   The rule does none of

those things.    It instead imposes a condition on the acceptance of

Medicare and Medicaid funds, thereby “regulating a federal pro-

gram.”     Florida, 19 F.4th at 1287 (emphasis added; citation omit-

ted).     The condition here no more violates Section 1395’s prohi-

bition on regulating the practice of medicine or the selection of

healthcare workers than do countless other conditions of Medicare

and Medicaid participation, such as detailed staff-qualification

and patient-treatment requirements.    See, e.g., 42 C.F.R. 482.22-

482.27.6

     B.     The Rule Is Not Arbitrary And Capricious

     Respondents alternatively contend that the vaccination rule

is arbitrary and capricious on various grounds.     None has merit.

     1.     Both district courts focused on one of respondents’

challenges in particular, which respondents renew here:     that the


     6    The Louisiana respondents assert (Opp. 13-15) that the
government forfeited its right to contest the district court’s
contrary interpretation of Section 1395, as well as certain other
issues, by not raising them in its stay application.      That is
mistaken. The Fifth Circuit did not endorse any of those alter-
native grounds for the preliminary injunction and instead rested
solely on circuit precedent addressing what the court called the
“major questions” doctrine. Louisiana Appl. App. 2a.
                                 20

Secretary allegedly failed to consider whether the rule will cause

staffing shortages.    Missouri Opp. 27-32; Louisiana Opp. 28-31.

But the Secretary extensively discussed the possible effects of

the rule on the labor market and ultimately found any risk of

short-term staffing shortages insufficient to outweigh the bene-

fits of the rule.   See 86 Fed. Reg. at 61,607-61,609.   Respondents

identify no sound basis to reject that judgment.

     In particular, the Secretary recognized the possibility that

the rule may cause “staffing and service disruptions” in cases

where “substantial” numbers of staff members refuse vaccination

and are not granted an exemption.     86 Fed. Reg. at 61,608.   But he

emphasized that such widespread departures had not actually come

to pass at healthcare facilities that had adopted vaccination re-

quirements.   Id. at 61,566, 61,569.      And he explained that any

such departures would be offset to some extent by reduced COVID-

related absenteeism and by the return to the labor force of indi-

viduals previously unwilling to work with unvaccinated colleagues.

Id. at 61,607, 61,609.     He also explained that any short-term

disruptions must be viewed in the overall context of the healthcare

labor market, where “it is normal for there to be roughly 2.66

million new hires” each year out of a labor force of 10.4 million.

Id. at 61,608.   He therefore concluded that “there is no reason to

think” that the rule will cause “a net minus” in staffing levels

“even in the short term.”     Id. at 61,609.     That conclusion was

amply supported by the evidence before the Secretary and accords
                                  21

with the views of leading organizations of healthcare profession-

als, none of which have supported respondents’ efforts to enjoin

the rule.     See Missouri Appl. 32-33; 86 Fed. Reg. at 61,565; see

also AMA Amici Br. 1-7; SEIU Amici Br. 1-2.

     Respondents contend (Missouri Opp. 28-29; Louisiana Opp. 29

& n.9) that declarations they submitted in litigation show that

the Secretary overlooked a distinct risk of staffing shortages in

rural areas.    But those declarations do not identify even a single

example of a vaccination requirement that triggered the sort of

widespread staff departure respondents predict.     The declarations

instead consist largely of reports indicating that some facilities

estimate or have been told that a subset of their unvaccinated

staff members would rather quit than be vaccinated.       See, e.g.,

Missouri Opp. App. 39a, 43a, 45a.        As the Secretary explained,

however, real-world experience shows that employees generally “re-

spond[] to mandates by getting vaccinated” rather than leaving

their jobs.    86 Fed. Reg. at 61,569.

     Respondents are mistaken in asserting that the evidence of

successful vaccination requirements involved only “urban areas.”

Missouri Opp. 29; see Louisiana Opp. 29.     For example, the Secre-

tary discussed the Novant Health system in North Carolina, see 86

Fed. Reg. at 61,566 n.132, which includes the “primary location[s]

for emergency and specialized services for people in rural commu-

nities” in that State, see Gina DiPietro, Novant Health, 5 Things

To Know (Feb. 1, 2021), https://perma.cc/L399-5VXC.       Similarly,
                                         22

the Secretary relied in part on evidence that a nursing facility

in “rural Alabama” that imposed a vaccine mandate “lost only six

of its 260 employees.”           Jack J. Barry et al., Half of Unvaccinated

Workers Say They’d Rather Quit Than Get a Shot -- But Real-World

Data       Suggest   Few   Are    Following     Through   (Sept.   24,   2021),

https://perma.cc/UDY2-F9ML; see 86 Fed. Reg. at 61,569 n.155.7

       That said, the Secretary seriously considered the concerns

respondents raise, acknowledging some “early indications” that

“rural hospitals are having greater problems with employee vac-

cination refusals than urban hospitals,” and inviting “comments on

ways to ameliorate this problem.”             86 Fed. Reg. at 61,613.    At the

same time, the Secretary noted that the need for the rule was

particularly strong in rural communities, where patients are es-

pecially at risk from COVID-19, id. at 61,566, and he ultimately

determined that the rule struck the appropriate balance based on

the evidence before him.           That quintessential policy judgment was

one for the Secretary, not States or the courts.            And the Secretary

was not required to wait for “perfect empirical or statistical

data” about the effects of the rule in rural areas before taking

steps to protect patients.           FCC v. Prometheus Radio Project, 141


       7  Public reports continue to confirm that concerns about
employees quitting en masse in response to COVID-19 vaccine man-
dates are generally overstated -- including in the respondent
States. See, e.g., Dave Muoio, Fierce Healthcare, How Many Em-
ployees Have Hospitals Lost to Vaccine Mandates? (Dec. 28, 2021),
https://perma.cc/E8LC-SQ4K (collecting reports of minimal staff
departures from healthcare facilities in Louisiana, Indiana, Kan-
sas, Kentucky, Ohio, South Carolina, and elsewhere).
                                  23

S. Ct. 1150, 1160 (2021); see, e.g., FCC v. Fox Television Sta-

tions, Inc., 556 U.S. 502, 521 (2009) (explaining that an “agency’s

predictive judgment    * * *   merits deference”).

      2.    This Court is also likely to reject respondents’ other

arbitrary-and-capricious challenges.

      First, respondents assert (Missouri Opp. 26; Louisiana Opp.

30) that the Secretary failed to adequately consider “testing” and

“natural immunity” (i.e., from a prior infection) as alternatives

to a vaccination requirement.    The Secretary explicitly considered

both, and his decision to reject those alternatives was fully

explained and reasonable.      For example, the Secretary found that

the “scientific evidence on testing” demonstrated that “vaccina-

tion is a more effective infection control measure,” 86 Fed. Reg.

at 61,614, and respondents have adduced no evidence to the con-

trary.     Likewise, the evidence before the Secretary supported his

conclusion that experiencing a COVID-19 infection is not equiva-

lent to receiving vaccination for COVID-19, and that, among those

persons with prior infections, vaccination provides stronger pro-

tection against reinfection.     Id. at 61,559-61,560 & n.69.   That

conclusion is not undermined by the Secretary’s separate statement

that individuals who recover from COVID-19 are unlikely to be

“sources of future infections.”     Id. at 61,604; see Missouri Opp.

26.   The question before the Secretary was whether vaccination

provides superior protection.       Substantial scientific evidence
                                24

supported his decision not to carve out from the vaccine require-

ment healthcare staff who previously contracted COVID-19.   See 86

Fed. Reg. at 61,614 (noting that any such carve-out would be con-

trary to CDC recommendations and would require “standards that do

not now exist for reliably measuring the declining levels of an-

tibodies over time in relation to risk of reinfection”).

     Second, the Secretary also acknowledged and fully explained

the agency’s change from its prior approach of merely encouraging

vaccination, which experience had shown to be “insufficient to

protect the health and safety of individuals receiving health care

services” from covered facilities.   86 Fed. Reg. at 61,583.   The

fact that the Secretary issued the rule after the President an-

nounced multiple measures designed to combat the COVID-19 pandemic

in specific contexts within federal authority through requirements

encouraging or requiring vaccination hardly shows that the rule is

“pretextual.”   Missouri Opp. 27; Louisiana Opp. 30.   Respondents

provide no reason to doubt the Secretary’s conclusion that the

rule will protect vulnerable Medicare and Medicaid patients.   The

fact that the rule will also protect the general public -- as the

Secretary forthrightly explained, see 86 Fed. Reg. at 61,612 -- is

an additional virtue, not impermissible pretext.

     Finally, there is no merit to the Missouri respondents’ claim

(Opp. 25-26) that the Secretary relied only on evidence from long-

term-care facilities.   Although the Secretary explained that such
                                     25

facilities have produced the most extensive data on COVID-19 trans-

mission in healthcare settings, see 86 Fed. Reg. at 61,585, he

also relied on hospital data, see ibid.; see also id. at 61,557-

61,558.     And he explained that those facilities illustrated the

danger    of    COVID-19   transmission   in   healthcare   settings   more

broadly because they “engage many, if not all, of the same health

care professionals and support services” as the other covered fa-

cilities.      Id. at 51,585.   The Secretary was entitled to draw such

inferences from the available data, particularly in the “absence

of any countervailing evidence.”          Prometheus Radio Project, 141

S. Ct. at 1159.

     C.        The Secretary Validly Promulgated The Rule

     This Court is also likely to reject respondents’ attacks on

the procedures the Secretary employed to issue the rule.

     1.        In light of the ongoing pandemic and urgent danger to

patients, the Secretary had good cause to issue the rule as an

interim final rule with a comment period, rather than delaying it

for advance notice and comment. Missouri Appl. 36-37. Respondents

do not identify any sound reason to reject the Secretary’s finding

that the rule is “the minimum regulatory action necessary” to

protect the health and safety of Medicare and Medicaid patients,

86 Fed. Reg. at 61,613, or that “further delay in imposing a

vaccine mandate would endanger the health and safety of additional

patients,” id. at 61,584.        Indeed, even before the emergence of

the Omicron variant, the Secretary correctly anticipated that time
                                 26

was of the essence because of the “potential for new variants” to

cause outbreaks of the kind that had devastated Medicare- and

Medicaid-participating facilities earlier in the pandemic.       Id. at

61,583-61,584.

     Respondents also do not dispute that Medicare and Medicaid

beneficiaries are especially at risk.      Although “COVID-19 can af-

fect anyone,” “[a]ge remains a strong risk factor for severe COVID-

19 outcomes.”    86 Fed. Reg. at 61,566.   The population aged 65 or

older accounts for more than 80% of U.S. COVID-19 related deaths.

See ibid.     Social determinants of health such as poverty also

“increase risk of severe illness and death from COVID-19,” ibid.,

and Medicaid beneficiaries are by definition in low-income house-

holds.     And “individuals seeking health care services are more

likely to fall into the high-risk category.”    Id. at 61,568.   Those

considerations all underscore the need for urgency.

     Respondents nonetheless assert (Louisiana Opp. 31-33; Mis-

souri Opp. 33) that the two-month “delay” between the President’s

announcement in September and the issuance of the interim final

rule in November precludes any invocation of the good-cause ex-

ception.    In that timeframe, the Secretary prepared and issued a

73-page rule -- including a detailed cost-benefit analysis, 86

Fed. Reg. at 61,586-61,615 -- while also continuing to manage the

agency’s other efforts to address the country’s worst pandemic in

a century.    Respondents’ assertion (Louisiana Opp. 33) that the
                                27

agency could have prepared the rule, solicited comments, and re-

viewed and responded to those comments in two months seriously

misunderstands the demands of the rulemaking process.    See, e.g.,

Anne Joseph O’Connell, Agency Rulemaking and Political Transi-

tions, 105 N.W. L. Rev. 471, 513-514 (2011) (finding that the

average notice-and-comment rulemaking takes more than a year).

     Respondents also fail to demonstrate any prejudice from the

lack of a comment period because the Secretary already considered

the issues they raise.   Compare Missouri Opp. 33-34 (arguing that

lack of comment period prejudiced the States by depriving them of

the opportunity to submit information on potential staffing short-

ages), with 86 Fed. Reg. at 61,608-61,609 (considering, at length,

the issue of “staffing and service disruptions”).

     2.   The Louisiana respondents’ reliance (Opp. 18-22) on 42

U.S.C. 1395z is equally unavailing.   That provision instructs the

Secretary to “consult with appropriate State agencies and recog-

nized national listing or accrediting bodies” in determining con-

ditions of Medicare participation for some of the facilities cov-

ered by the rule, 42 U.S.C. 1395z, but it does not require that

such consultations occur in advance of any rulemaking.   See Flor-

ida, 19 F.4th at 1290 n.3.     To the contrary, the consultation

requirement should be construed in light of the Medicare statute’s

express authority for the Secretary to adopt “interim final regu-

lations,” which may be made effective immediately for good cause.

42 U.S.C. 1395hh(a)(3)(C); see 42 U.S.C. 1395hh(b)(2)(C).      The
                                 28

Secretary expressly found that delaying the vaccination rule --

including for advance consultations with States -- would jeopard-

ize the lives and health of patients.     86 Fed. Reg. at 61,567.

The Secretary therefore reasonably determined to engage in the

requisite consultations after issuing the rule.   See ibid.

     3.    The Louisiana respondents also err in relying (Opp. 16-

18) on 42 U.S.C. 1302(b), which requires the preparation of a

regulatory impact statement for some rules that may affect a sub-

stantial number of small rural hospitals.      By its terms, that

statute does not apply to interim final rules like the one at issue

here.     Section 1302(b)(2) requires the preparation of a final

regulatory impact analysis “[w]henever the Secretary promulgates

a final version of a rule or regulation with respect to which an

initial regulatory impact analysis is required by paragraph (1),”

42 U.S.C. 1302(b)(2), which in turn applies only to the publication

of proposed rules.    And in any event, the Secretary determined

that the rule “will not have a significant impact on the operations

of a substantial number of small rural hospitals.”    86 Fed. Reg.

at 61,613.

III. The Remaining Factors Overwhelmingly Favor A Stay

     The remaining considerations overwhelmingly favor granting a

stay to allow the rule to protect Medicare and Medicaid patients

while the appeals are pending.    The preliminary injunctions were

imposed right as the highly transmissible Omicron variant emerged
                                 29

and at the beginning of the winter holiday season, with its pre-

dictable increases in travel and indoor social gatherings.      The

explosion in COVID-19 cases that has resulted from those develop-

ments has severely strained the Nation’s healthcare system and

heightened the danger to vulnerable Medicare and Medicaid pa-

tients.

       On the other side of the ledger, it bears repeating that the

rule has been challenged only by States, not any private facilities

impacted by the rule -- or their workers, who may seek medical or

religious exemptions.    And the interests the States assert do not

support the sweeping relief granted by the district courts.      Re-

spondents focus almost exclusively on an asserted risk of labor

shortages in “rural” areas (e.g., Missouri Opp. 1, 2, 6, 7, 29,

37).    But that risk is, at best, highly speculative.   See pp. 20-

23, supra.    And it would be profoundly inequitable to deprive all

Medicare and Medicaid patients in the respondent States of the

rule’s protection based on speculative concerns about some rural

labor markets.

       The Louisiana respondents also err in asserting (Opp. 35-37)

that a stay pending appeal would be tantamount to granting “ulti-

mate relief,” on the theory that employees who become vaccinated

during litigation cannot be unvaccinated afterwards if respondents

prevail.    That assertion misapprehends the operation of the rule,

which specifies a condition of participation for facilities.      A

facility that wishes to challenge the mandate may do so -- subject
                                    30

to the statutory channeling provision, see Missouri Appl. 39 --

and the “ultimate relief” available to the facility if it were to

prevail would be the reversal of any sanctions imposed for non-

compliance.    In short, granting a stay pending appeal may save

hundreds or thousands of lives and would not preclude granting

meaningful relief in the unlikely event that respondents ulti-

mately prevail.

                          *    *    *    *   *

     For the foregoing reasons and those stated in the government’s

applications, the injunctions should be stayed pending appeal and,

if the Fifth or Eighth Circuit affirms the relevant injunction,

pending the filing and disposition of a petition for a writ of

certiorari and any further proceedings in this Court.      At a mini-

mum, the injunctions should be stayed as to all facilities other

than those operated by respondents.

     Respectfully submitted.

                                   ELIZABETH B. PRELOGAR
                                     Solicitor General

JANUARY 2022


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